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Authors' response to ’Comment on ’Effects of injectable progestogen contraception versus the copper intrauterine device on HIV acquisition: sub-study of a pragmatic randomised controlled trial' '
  1. G Justus Hofmeyr1,
  2. Theresa Anne Lawrie2,3
  1. 1 Effective Care Research Unit, Eastern Cape, Department of Health, Universities of the Witwatersrand, Walter Sisulu and Fort Hare, East London, South Africa; justhof@gmail.com
  2. 2 Effective Care Research Unit, Eastern Cape, Department of Health, Universities of the Witwatersrand, Walter Sisulu and Fort Hare, East London, South Africa
  3. 3 Royal United Hospital, Bath, UK; tess@lawrie.com
  1. Correspondence to Dr Theresa Anne Lawrie; tess{at}lawrie.com

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We thank Quispe Calla and colleagues for their insightful comments1 on our article.2 We agree that basic science evidence showing that various progestogens increase HIV susceptibility is compelling. We also agree that randomised clinical trials (RCTs) are informative regarding the relative risks of HIV between contraceptive alternatives, but not the absolute risks …

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